The nRF9161 DK is equipped with a RESET button (SW5).
By default, the RESET button is connected to the interface MCU and an analog switch Integrated Circuit (IC). The RESET signal is forwarded from the interface MCU to the nRF9161 System in Package (SiP) or any device connected to the external debugging and programming connectors. If the interface MCU is disabled, the RESET button is connected directly to the SiP.